Tamgo
Advanced alpha-1A selective adrenoceptor antagonist in prolonged-release formulation for effective management of lower urinary tract symptoms (LUTS) associated with Benign Prostatic Hyperplasia (BPH).
What is Tamgo?
Tamgo is a branded pharmaceutical product by Inspiron Scientific Pvt. Ltd. containing Tamsulosin Hydrochloride 0.4mg in prolonged-release tablet form. Tamsulosin is a highly selective alpha-1A adrenoceptor antagonist that specifically targets the smooth muscle of the prostate gland, bladder neck, and prostatic urethra to relieve lower urinary tract symptoms (LUTS) associated with Benign Prostatic Hyperplasia (BPH).
The prolonged-release formulation ensures consistent drug release over 24 hours, maintaining steady therapeutic plasma concentrations for all-day symptom relief with just one tablet daily. Tamsulosin’s high selectivity for alpha-1A receptors means it effectively relaxes prostate smooth muscle with minimal impact on blood pressure, making it one of the most well-tolerated treatments for BPH worldwide.
Detailed Product Information
Everything healthcare professionals and patients need to know about Tamgo — from composition and mechanism of action to clinical benefits and administration guidelines.
• Tamsulosin Hydrochloride 0.4mg
Dosage Form: Prolonged-Release Tablets
Release Technology: Modified Release (MR)
Route: Oral Administration
Category: Alpha-1A Adrenoceptor Antagonist
Marketed by: Inspiron Scientific Pvt. Ltd.
By blocking these receptors, Tamsulosin relaxes the smooth muscle in these areas, reducing urethral resistance and improving urine flow without significantly affecting blood pressure — unlike non-selective alpha blockers.
The prolonged-release formulation provides consistent plasma levels over 24 hours for sustained symptom control.
- Difficulty in initiating urination (hesitancy)
- Weak or interrupted urine stream
- Frequent urination (increased frequency)
- Urgency — sudden strong need to urinate
- Nocturia (nighttime urination)
- Sensation of incomplete bladder emptying
- Straining during urination
- Rapid symptom relief — noticeable improvement in urinary symptoms within 1–2 weeks of treatment
- Improved peak urinary flow rate (Qmax) — clinically significant increase in urine flow
- Significant improvement in IPSS scores (International Prostate Symptom Score)
- High alpha-1A selectivity — minimal impact on blood pressure; no need for dose titration
- Prolonged-release formulation — steady drug levels over 24 hours for consistent all-day relief
- Well-established global safety profile — one of the most prescribed alpha blockers worldwide
Administration: Take approximately 30 minutes after the same meal each day (preferably after breakfast). Swallow whole with a glass of water — do not crush, chew, or break the tablet as this destroys the prolonged-release mechanism.
Dose Titration: No dose titration is required. Start directly with 0.4mg once daily.
Missed Dose: If a dose is missed, skip it and take the next dose at the usual time. Do not double the dose.
Duration: As directed by the physician. Long-term use is generally required for sustained benefit.
Packaging: Available in alu-alu blister pack for optimal product protection and stability.
Shelf Life: As mentioned on the pack. Do not use after the expiry date.
Disposal: Do not dispose of unused tablets in household waste or wastewater. Consult your pharmacist for proper disposal methods.
Understanding Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia (BPH) is a common, non-cancerous enlargement of the prostate gland that affects men as they age. The prostate surrounds the urethra, and when it enlarges, it can squeeze or partially block the urethra, leading to bothersome lower urinary tract symptoms (LUTS) that can significantly impact quality of life if left untreated.
BPH is not prostate cancer and does not increase the risk of cancer. However, it can cause considerable discomfort and inconvenience. The dynamic component of BPH — increased smooth muscle tone mediated by alpha-1A adrenergic receptors — is the primary target of Tamgo (Tamsulosin HCl 0.4mg), which selectively relaxes these muscles to restore normal urine flow.
Common Symptoms of BPH
Recognizing the signs early can lead to timely treatment and better outcomes. Consult your doctor if you experience any of the following:
How Tamgo Helps
Tamgo works through a targeted mechanism to deliver rapid and sustained symptom relief by selectively acting on prostate alpha-1A receptors.
- Take Tamgo only as prescribed by your doctor
- Always take approximately 30 minutes after the same meal each day (preferably breakfast)
- Do not crush, chew, or break the tablet — swallow whole to maintain prolonged-release properties
- May cause dizziness or lightheadedness, especially when standing up quickly — rise slowly from sitting or lying position
- Inform your doctor about all current medications, including herbal supplements and over-the-counter drugs
- Use caution while driving or operating machinery if you experience dizziness
- Inform your ophthalmologist about Tamsulosin use before any planned eye surgery (Intraoperative Floppy Iris Syndrome may occur)
- Not intended for use in women or children
- If symptoms worsen or do not improve after several weeks of treatment
- If you experience blood in urine, painful urination, or inability to urinate
- If you have a history of low blood pressure (orthostatic hypotension)
- If you have severe liver or kidney impairment
- Before any planned eye surgery (especially cataract surgery)
- If you experience prolonged dizziness, fainting, or palpitations
- If you are taking other medications for blood pressure or prostate conditions
- If you have a known allergy to Tamsulosin or sulfonamides
- If you experience any allergic reactions such as rash, swelling, or difficulty breathing
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